Chronic Wound Infection

Junior (College 3rd year) ・Healthcare&Medicine ・APA ・1 Sources

In the “Approach to Chronic Wound Infections,” Leaper, Assadian and Edmiston contend that chronic wounds are associated with decreased quality of life, high cost of treatment and management and lower productivity. Therefore, health providers should gain a deeper insight into tenets of wound care and present diagnostic modalities in order to lower costs and enhance patient outcome. Infection is the common complication of chronic open wounds, which cause delayed healing. The persistence of wound colonization by bacteria and the long term use of antimicrobials influence the development of infections. While there is variety of antimicrobials infection prevention, the rise of antibiotic resistance complicates the healing process even more. The progression of Chronic wounds result in a more serious deep organ infection that may be life-threatening (Leaper, Assadian & Edmiston, 2015). Chronic wounds like arterial ulcers, diabetic foot ulcers and pressure sores facilitate biofilm formation.
The presence of biofilms contributes to further delay in healing by causing excessive inflammation. Because biofilm is clinically undetectable, a diagnostic is considered necessary. One of the wound Management strategies is controlling biofilm. It is for this reason that the basic precept on treatment of open wounds focuses on effective debridement and antiseptics in order to prepare the wound for healing. According to the authors, antibiotics should be reserved owing to the rising antimicrobial resistance. Existing evidence does not encourage the use of systematic antimicrobials to treat or prevent wound infection. This is because the approach gives rise to antibiotic resistance. Current guidelines of wound biofilm infection propose debridement and antiseptics. The authors conclude by suggesting that there is need to develop a biofilm diagnostic to help fingerprint the presence of pathogens in wounds in terms of types and their number.


Leaper, D., Assadian, O., & Edmiston. (2015). Approach to chronic wound infections. British Journal of Dermatology, 173; 351-358

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