Intraoperative Allogeneic Red Blood Cell Transfusion and Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

Junior (College 3rd year) ・Healthcare&Medicine ・MLA

The article conducts a study of patients undergoing valve surgery, Coronary Artery Bypass Graft (CABG) or a combination of the two conditions between 2010 and 2014. The sample size for the study was 2,978 patients, and the mean was 66.4 years. The age of the patient use in the study was 15 years and above, and the researchers had both consent from the hospital and the participant. The mode of selecting the patients was non-random as the researchers were interested in patients who underwent valve or CABG surgery. Moreover, the researchers used chi-square tests sampling method for homogeneity and to help determine if the sample frequencies of the research differ in any way.

Type of study

The kind of the study is prospective this is because the investigators look at the outcomes such as the development of the condition during the time of the survey and compare the results with other suspected results. Moreover, the fact that the survey took four years makes it a prospective research. The study was anonymous because the researchers did not take confidential information, so there was no way they could link the results to the individual participation. The study is quantitative because it gathers numerical data which the researchers can put into categories and measure. The study was experimental as it was aimed at provided a definitive conclusion about the relationship between intraoperative allogeneic RBC transfusion and POAF in cardiac surgery.

The independent variables are the variables that can be changed. The independent variable in the study is valve surgery and CABG. The dependent variable are the variables that are being measured, and for the study, they include the time between 2010 and 2014 and the number of participants which is 2,978. The study did not have a confounding variable as the researchers were only interested in patients who had undergone valve of CABG surgery. The study used repeated measure measures experimental research design as all the participants took part in each of the independent variables. This means that all the members have tested for each condition the experiment.

The study was done through linkage between the hospital administrative database and system at an individual level. Moreover, the study was a proved by the Danish Data Protection Agency. The study mainly relied on the data collected from the database and system of the linked hospitals. The study made use of data usage as an instrument of gathering information. The instrument used for the study were valid. Moreover, the instrument was reliable, and they produced consistent results for the study.


The methods used for statistical analysis for the study included mean, standard deviation, and percentage. The measure of central tendency used is mean. The standard deviation of the results was 8.8. The distribution of the results was a normal distribution. The results were significant as they helped the clinicians understand the reoccurrence. There was no significant error, and the statistics were not biased. 


The problem of the study included that the patients receive transfusion preoperatively. Consequently, there still the risk of confining. Therefore, the method used for obtaining was no used on patients until discharge."

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