The Genes And Somatic Gene Cells
Method of Gene Therapy
Gene therapy involves a process of including genes and somatic gene cells into someone's cells and tissues to treat a disease. A defective allele is changed with a functional one so as to treat a disease. The method of somatic gene therapy will involve correcting a sickness in a patient affected by a genetic situation by inserting a normal gene into the suitable cells of the patient. The target cell may be cells found in the bone which are easily remoted and re-implanted. This paper involves the methods used in gene therapy.
Use of Vectors in Gene Therapy
The genes are inserted into the focused cells, and one way is the use of vectors. A vector is used as a transporter for the genetics, and it helps it to enter into the targeted cell with ease depending on the type of the vector. These vectors are administered so as to target specific cell types. Vectors are used as a carrier of the new genes into the targeted cells.
Ex Vivo Somatic Gene Therapy
Ex vivo somatic gene therapy is one of the principal ways on how a vector can be administered whereby the target cells are removed from the body, this target cell will be cultured in the laboratory using a vector, and then it will be reinstated back in the body (Friedman 95). This method is done using the blood cells which are most comfortable to remove and then return again to the body.
In Situ Somatic Gene Therapy
Another way is the in situ somatic gene therapy whereby the vector is placed directly into the tissue which is affected and is developed way to treat cystic fibrosis and to treat muscular dystrophy (Anderson 278).
In Vivo Somatic Gene Therapy
The last method which can be used is in vivo somatic gene therapy whereby the vector is inserted directly into the bloodstream. When the vector is inserted straight, it is able to find the cells which it was explicitly designed. The vectors used can either be viral or non-viral (Miller 271).
Works Cited
Anderson, W. French. "Human gene therapy: scientific and ethical considerations." The Journal of medicine and philosophy 10.3 (1985): 275-292.
Friedmann, Theodore. "A brief history of gene therapy." Nature genetics 2.2 (1992): 93-98.
Miller, A. Dusty. "Progress toward human gene therapy." Blood76.2 (1990): 271-278.
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